About binding proteins

"Binding Proteins are next-generation fermented IgG fragments designed for precision and gut resilience."

Introduction to Binding Proteins

Being able to safeguard your gut is critical to staying healthy: Like infants are protected by IgGs in mother’s milk, Binding Proteins have the potential to support the large populations world wide from unhealthy metabolites or enterotoxins.

Unlike broad-spectrum immunity ingredients, they selectively bind to unhelathy metabolites (toxins), supporting gut balance without disrupting the microbiome. With a vegan-friendly profile and proven efficacy at low daily intake, Binding Proteins offer a science proven Mode of Action to immune and digestive health.

Binding Protein Research

Binding Proteins Origin

It was discovered in 1993 that immunoglobulins (IgG) from camelids (camels, alpacas etc.) have a simple structure, and a binding domain comprising a single polypeptide chain, making it a small stable protein with a targeted binding activity.

Precision Fermentation

Binding Proteins are manufactured using established food industry best practices, including established (GRAS) microbial expression methods, adherence to Good Manufacturing Practices (GMP), and Hazard Analysis and Critical Control Points (HACCP)Protocols.

Mode of Action

Each unique Binding Protein specifically binds to selected unhealthy metabolites (toxins), facilitating their safe and gentle passage through the GI-tract. While antibiotics eliminate bacteria in the gut, Binding Proteins have no kill effect, and do not cross the gut epithelial barrier or activate the immune system, and have a fast onset of action with effects observable shortly after ingestion.

"Each Binding Protein specifically binds to selected microbial toxins, undesired metabolites, or microbes facilitating their safe and gentle passage through the gastrointestinal tract."

Timeline infographic showing the evolution of camel-derived immunoglobulin research from 5000 years ago to 2025. The timeline includes key milestones: camel milk consumption in arid regions for thousands of years, 1990-1995 discovery of camelid antibacterial and antiviral properties, 1993 discovery of unique camelid immunoglobulins with simple structures and targeted binding activity, 2005-2015 studies on camelid immunoglobulin stability properties including heat resistance, 2020-2023 discovery of binding proteins supporting gut microbiome health, and 2023-2025 development of IgG binding proteins through precision fermentation with toxicology studies demonstrating safety for food and beverage applications.Timeline infographic showing the evolution of camel-derived immunoglobulin research from 5000 years ago to 2025. The timeline includes key milestones: camel milk consumption in arid regions for thousands of years, 1990-1995 discovery of camelid antibacterial and antiviral properties, 1993 discovery of unique camelid immunoglobulins with simple structures and targeted binding activity, 2005-2015 studies on camelid immunoglobulin stability properties including heat resistance, 2020-2023 discovery of binding proteins supporting gut microbiome health, and 2023-2025 development of IgG binding proteins through precision fermentation with toxicology studies demonstrating safety for food and beverage applications.
Introducing Giga Binding Units (gBU): A Functional Measurement Standard for Immunoglobulin Ingredients

Introducing Giga Binding Units (gBU): A Functional Measurement Standard for Immunoglobulin Ingredients

Walk into any supplement retailer or browse online marketplaces for immunoglobulin products, particularly IgG and IgY, and you will notice something striking. Products making similar digestive and immune health claims recommend vastly different daily servings; one product suggests 200mg, another suggests 2,500mg, over 12 times higher. This variation makes it difficult for consumers to evaluate product value, for formulators to select ingredients and establish serving sizes, and for researchers to compare outcomes across studies. For a category valued at more than $5 billion and growing at a CAGR of more than 7%, this is a challenge worth solving.

Gut Dysbiosis Uncovered: How Gut Diversity & Gut Barrier Function Play a Crucial Role in Maintaining Your Health 

Gut Dysbiosis Uncovered: How Gut Diversity & Gut Barrier Function Play a Crucial Role in Maintaining Your Health 

The human gut microbiota plays a pivotal role in maintaining overall health. When the composition and function of this microbial ecosystem become imbalanced, we talk about gut dysbiosis. This imbalance contributes to a dysregulated gut-immune axis, referring to impaired communication and feedback loop between the gut microbiota, intestinal barrier, and the immune system¹.

A New Gut Sense: How Microbial Cues May Quickly Shape Appetite

Imagine you’re about to eat, and then your appetite simply fades. What might have happened? One possibility involves microorganisms living in the gut. The intestinal microbiota can engage gut–brain neural circuits, but the molecular mechanisms mediating these interactions remain incompletely understood.